Publication Sabrina Müller Publication Sabrina Müller

Association between asthma control and healthcare costs: Results from a German linked data study

This study aimed to evaluate differences in healthcare resource utilization and cost among patients with controlled and uncontrolled asthma. Claims data from a German sickness fund was linked to patient survey data. Outpatient physicians enrolled patients and assessed asthma control using the ACT questionnaire. All-cause and asthma-specific healthcare resource use (HCRU)/costs were compared descriptively and based on multivariable models using a continuous ACT score.

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Publication Sabrina Müller Publication Sabrina Müller

Questionnaire for the assessment of adherence barriers of intravitreal therapy: the ABQ‑IVT

The previously validated (indications: atrial fibrillation, human immunodeficiency virus, chronic inflammatory lung disease) Adherence Barriers Questionnaire (ABQ) was revised according to specifications of IVT, within the framework of an expert panel. A cross-sectional patient survey was conducted in combination with a retrospective medical chart review in order to validate the developed new instrument (ABQ-IVT).

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Publication Sabrina Müller Publication Sabrina Müller

Identifying the Causes Increasing the Risk of Non‑Adherence in Adult Patients with Asthma: An Analysis Combining Patient Survey Data with German Claims Data

A multi-center observational study was conducted addressing adult patients with asthma who were prescribed regular maintenance medication between 2014 and 2016 to identify the potential barriers to medication adherence among adult patients with asthma in Germany. Data were derived from physicians’ documentation and claims data, which were linked to the primary observational data and patient survey data (Adherence Barriers Questionnaire - ABQ).

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Adaption and validation of the adherence barriers questionnaire for HIV patients on antiretroviral therapy (ABQ-HIV)

The aim of this investigation was to develop and validate a respective questionnaire (Adherence Barriers Questionnaire for HIV: ABQ-HIV), based on an earlier version of the ABQ.

The study showed that the ABQ-HIV is a practical, reliable, and valid instrument for identifying patient-specific barriers to

adherence in the HIV treatment that is also useful in identifying HIV patient subgroups.

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Treatment of age-related neovascular macular degeneration:the patient’s perspective

The aim of this study was to assess patients’ views and xpectations with regard to neovascular age-related macular degeneration (nAMD) and intravitreal anti-VEGF therapy (IVT).

This multicenter, non-interventional, prospective cohort study showed that only a minority of patients are aware of the chronic nature of nAMD. To motivate patients to accept a life-long IVT treatment, physicians and caregivers must know that there exist different patient types with significant differences in communication needs.

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Publication Sabrina Müller Publication Sabrina Müller

Nonadherence in Outpatient Thrombosis Prophylaxis with Low Molecular Weight Heparins after Major Orthopaedic Surgery

According to some current guidelines, extended thromboprophylaxis after hip and knee arthroplasties is recommended. Outpatient prophylaxis with low molecular weight heparins (LMWH) is an important part of this prophylaxis, although the rates of adherence to these regimens are unknown. We determined (1) the degree of nonadherence (NA) of patients with LMWH outpatient prophylaxis and (2) whether specific independent factors explain NA.

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